<strong>Abstract</strong> <em>Introduction: </em>Craniopharyngiomas have been classically removed by various transcranial approaches (craniotomy). Nowadays with the advance in endoscope transsphenoidal surgery, the extended transsphenoidal approach is the best choice for removal of suprasellar tumors and even intra-ventricular craniopharyngiomas. However, this is still challenging to surgeons in removing the tumors by this approach and the surgical complications could be occurred. <em>Material and Methods: </em>From 7/2013 – 7/2017, 50 patients (39 adults and 11 children) underwent surgery for craniopharyngioma by nasal transsphenoidal approaches. The complications regarding the surgery was recorded. <em>Results: </em>The early postoperative mortality was 2/50 (4%) caused by meningitis, intra-ventricular hemorrhage. The epidural hematoma was 1/50 (2%); Meningitis 6/50 (12%); Cerebrospinal fluid (CSF) leakage occurred in 3/50 (6%); Hypothalamus damage was 1/50 (2%), Visual deterioration was 3/50 (6%) <em>Conclusion: </em>Almost Craniopharyngioma have been removed successfully by endoscope transsphenoidal surgery. However, still the surgical complication rate was related high such as meningitis, visual deterioration, CFS leakage and postoperative mortality rate recorded. <strong>Keyword: </strong>Craniopharyngioma; Suprasellar tumors; endoscope transsphenoidal surgery. <strong>References</strong> <ol> <li>Cappabianca, P., Tschabitscher, M, Extended endoscopic endonasal transsphenoidal approach to the suprasellar area: anatomic considerations e part Neurosurgery 2007. 61.</li> <li>Cavallo, L.M., Prevedello, D.M., Solari, D., Gardner, P.A., Esposito, F., Snyderman, C.H., Carrau, R.L., Kassam, A.B., Cappabianca, Extended endoscopic endonasal transsphenoidal approach for residual or recurrent craniopharyngiomas. J. Neurosurg, 2009(111): p. 578-689.</li> <li>De Divitiis, E., Cappabianca, P., Cavallo, L.M., Esposito, F., De Divitiis, O., Messina, A, xtended endoscopic transsphenoidal approach for extrasellar craniopharyngiomas. Neurosurgery, 2007(61): p. 219-227.</li> <li>Elliott, R.E., J. John A. Jane, and J.H. Wisoff, Surgical Management of Craniopharyngiomas in Children: Meta-analysis and Comparison of Transcranial and Transsphenoidal Approaches. Neurosurgery, 2011. 69: p. 630–643.</li> <li>Elliott, R.E., et al., Efficacy and safety of radical resection of primary and recurrent craniopharyngiomas in 86 children. Journal of Neurosurgery: Pediatrics, 2010. 5(1): p. 30-48.</li> <li>Fahlbusch, R., Honneger, J., Buchfelder, Transsphenoidal microsurgery for craniopharyngiomas. Shmidek and Sweet Operative neurosurgical techniques. Indications, methods, and results, 2000(W. B. Saunders, Philadelphia</li> <li>Frank, G., Pasquini, E., Doglietto, F., Mazzatenta, D., Sciarretta, V., Farneti, G., Calbucci, A, The endoscopic extended transsphenoidal approach for craniopharyngiomas. Neurosurgery, 2006(59): p. 75-83.</li> <li>Gardner, A., Prevedello, D.M., Kassam, A.B., Snyderman, C.H., Carrau, R.L., Mintz, A.H, The evolution of the endonasal approach for craniopharyngiomas. J. Neurosurg, 2008(108): p. 1043-1047.</li> <li>Karavitaki, Management of craniopharyngiomas. J. Endocrinol. Invest, 2014(37): p. 219-228.</li> <li>Kassam A, G.P., Ricardo L. Carrau, Snydermann C, et al Endoscopic reconstruction of th cranial base using a pedicled nasoseptal flap. Neurosurgery 2008(63): p. 44-53.</li> <li>Kassam, A.B., Thomas, A., Carrau, R.L., Snyderman, C.H., Vescan, A., Prevedello, D., Mintz, A., Gardner, P, Endoscopic reconstruction of the cranial base using a pedicled nasoseptal flap. Neurosurgery, 2008(63): p. 44-52.</li> <li>Komotar, R.J., Starke, R.M., Raper, D.M., Anand, V.L., Schwartz, T.H, Endoscopic endonasal compared with microscopic transsphenoidal and open transcranial resection of craniopharyngiomas. World Neurosurg, 2012(77): p. 329-341.</li> <li>Komotar, R.J., et al., Endoscopic endonasal versus transsphenoidal microscopic and open transcranial resection of craniopharyngiomas: a systematic meta-analysis of outcomes. Skull Base, 2011. 21(S 01): p. A141.</li> <li>Koutourousiou, M., Gardner, P.A., Fernandez-Miranda, J.C., Tyler-Kabara, E.C., Wang, E.W., Snyderman, C.H, Endoscopic endonasal surgery for craniopharyngiomas: surgical outcome in 64 patients. J.Neurosurg, 2013(119): p. 1194-1207.</li> </ol> <!--more--> <a href="https://vjsel.vn/wp-content/uploads/2021/02/SỐ-4-TẬP-9-2019-chot-In-37-50.pdf">Download PDF File</a>
Nguyễn Thanh XuânKiều Đình Hùng Nguyễn Thanh XuânKiều Đình Hùng