Abstract
Introduction: Laparoscopic liver resection is a challenging procedure, yet it is increasingly applied in the treatment of hepatocellular carcinoma (HCC), including our center. Our aim is to evaluate the impact of laparoscopic hepatectomy for hepatocellular carcinoma regarding the long-term outcomes.
Patients and Methods: A combined retrospective-prospective cohort study of 41 HCC patients who underwent laparoscopic hepatectomy at the Organ Transplantation Center, Viet Duc University Hospital from January 2019 to December 2023.
Results: Liver resection for tumors >5 cm accounted for 24.4%, with 63.4% of cases classified as high difficulty (Ban Daisuke score). The mean operative time was 192 minutes, and the intraoperative blood transfusion rate was 18.9%. The mean disease-free survival was 44.5 ± 3.19 months, with 1-, 2-, 3-, and 4-year rates of 94.4%, 87.2%, 70.6%, and 70.6%, respectively. The mean overall survival was 50.0 ± 2.30 months, with corresponding rates of 96.7%, 92.9%, 86.8%, and 86.8%. Preoperative AFP <400 ng/mL and resection margin >0.5 cm were favorable prognostic factors.
Conclusions: Laparoscopic hepatectomy is a safe and effective treatment option for hepatocellular carcinoma offering significant survival benefits.
Keywords: Laparoscopic hepatectomy, Difficulty Scoring System, Hepatocellular carcinoma.
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