Abstract
Introduction: Gallbladder carcinoma (GBC) is a rare but aggressive tumor. Operability is crucial for survival, yet late-stage diagnosis is common due to its asymptomatic nature. This study evaluates the clinical features and surgical outcomes of GBC treatment.
Patients and Methods: A retrospective study was conducted on GBC patients who underwent surgery at Viet Duc University Hospital (2015–2022). Inoperable cases and those with incomplete records were excluded. Clinical characteristics, surgical details, and outcomes were analyzed.
Results: Among 41 patients, most were diagnosed at advanced stages, with T3 being the most common stage (51.2%). Open surgery (51.2%) was slightly more frequent than laparoscopic procedures. Cholecystectomy alone was performed in 31.7%, while others required hepatectomy or lymphadenectomy. The average hospital stay was 8 ± 3.5 days, with complications occurring in 3 cases and one postoperative death. Mid-term survival was poor, with 31.7% surviving less than six months and 29.3% living for 1–3 years.
Conclusions: GBC is often diagnosed late, limiting surgical success and survival. Despite surgical resection, prognosis remains poor, highlighting the need for earlier detection and improved treatment strategies.
Abbreviations: GBC: Gallbladder carcinoma, CT: Computed tomography, MRI: Magnetic resonance imaging, CA 19-9: Carbohydrate antigen 19-9, CEA: Carcinoembryonic antigen
Keywords: Gallbladder cancer, surgical treatment, mid-term survival
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